Connectivity problems like "connect() failed (111: Unknown error)" can occur while utilizing Odoo 16 with Nginx as a reverse proxy on Ubuntu 22. This can impact real-time capabilities like websocket communication. This error frequently denotes issues with websocket configurations necessary for Odoo's data retrieval or Nginx timeout settings. Reliable connections may be ensured by configuring Nginx's proxy_connect_timeout and proxy_read_timeout settings.